關於 statin potency ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. Statin therapy in patients with acute coronary syndrome

Statin therapy in patients with acute coronary syndrome: low-density lipoprotein cholesterol goal attainment and effect of statin potency ...

#12. Prescribing statins to reduce cardiovascular risk - bpacnz

Pravastatin (lowest potency statin) is associated with the lowest risk of developing new onset diabetes mellitus, atorvastatin has moderate risk ...

#13. Statin 類降血脂藥品與糖尿病的糾葛

另一篇於2014 年發表，類似的大型觀察性及meta-analysis 綜合研究，也發現高強度的statin (High potency: rosuvastatin ≥10 mg, atorvastatin ≥20 mg,simvastatin ...

#14. Potency Of Statins Linked To Muscle Side Effects

Their use has been linked to a variety of muscle-related side effects (together termed “statin myopathy”) that occur in as many as 10 to 15 ...

#15. A Retrospective Study of Statin Use and Its Effectiveness in ...

statins were medium potency such as atorvastatin 10 mg (93.4%), fluvastatin 80 mg (96.7%), ... Key Words: Lipid lowering · Statin · Coronary heart disease.

#16. Statin Potency and the Risk of Hospitalization ... - ResearchGate

However, it is unclear if these purported benefits vary with statin potency. Our objective was to determine if higher potency statins, compared with lower ...

#17. Hydrophilic or Lipophilic Statins? | Cardiovascular Medicine

According to their solubility, statins can be categorised as hydrophilic and lipophilic. The predominantly lipophilic statins (simvastatin, ...

#18. Therapeutic practice patterns related to statin potency and ...

BACKGROUND: Statin combination therapy and statin uptitration have been shown to be efficacious in low-density lipoprotein cholesterol (LDL-C) lowering and ...

#19. Discovery of a potent HMG-CoA reductase degrader ... - Nature

Statins are inhibitors of HMG-CoA reductase, the rate-limiting enzyme of cholesterol biosynthesis, and have been clinically used to treat ...

#20. Statin - Wikipedia

LDL-lowering potency varies between agents. Cerivastatin is the most potent, (withdrawn from the market in August, 2001 due to risk of serious rhabdomyolysis) ...

#21. Considerations in the Approach to Appropriate Statin Selection

ABSTRACT: Statins are a class of medications widely used for primary and secondary prevention of cardiovascular events.

#22. Effect of high-potency statins on HbA1c in patients with or ...

The increased risk of new-onset diabetes with statin use, including high-potency statins, is well known. However, the effects of ...

#23. Dyslipidaemias | Treatment summary - BNF - NICE

Statins are the drugs of first choice for treating hypercholesterolaemia and ... Fenofibrate may be added to statin therapy if triglycerides remain high ...

#24. Comparison between high and low potency statins in ... - PLOS

According to a previous study [21], the statins were classified as 'low potency statin' (pravastatin, fluvastatin, pitavastatin, and simvastatin) ...

#25. 高危險群門診病患Statin 類藥物治療型態與費用效益評估

potency dose statins. (low equipotency-10 mg simvastatin、40 mg fluvastatin , medium equipotency-5 mg rosuvastatin、10 mg atorvastatin、20 mg.

#26. [臨床藥學] Statin類藥品降血脂效果速算表(Reductions in LDL ...

NEJS · [臨床藥學] Statin類藥品降血脂效果速算表(Reductions in LDL Cholesterol Concentrations with Different Doses of Statins).

#27. 臺灣醫學會

S10-3. Cons: No more target but statin potency 林宗憲高雄醫學大學附設醫院心臟血管內科. Dyslipidemia is one of the major causes of atherosclerosis and ...

#28. Statin potency and the risk of hospitalization for ... - Meta.org

Our objective was to determine if higher potency statins, compared with ... A total of 217 721 patients entered the cohort on a lower potency statin and 130 ...

#29. Clinical Efficacy and Safety of Evolocumab in High-Risk ...

Of 7533 patients (27.3%) receiving maximal-potency statins, ... as in the 20 031 patients not receiving a maximal-potency statin (HR, 0.85; ...

#30. Airiti Library華藝線上圖書館_Statin-Associated+Adverse+Events

HMG-CoA reductase inhibitor ； statin ； myopathy ； cognitive impairment ... Incident diabetes remains difficult to predict, but high statin potency, ...

#31. Early treatment with high-potency statins in patients with acute ...

low potency statins in ACS was examined by the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22 (PROVE IT- ...

#32. Pharmaceutical strategies for reducing LDL-C and risk of ...

High-potency statins should be used in patients with the greatest CVD risk [4]. Furthermore, prolonged statin therapy leads to the greatest reduction of CVD ...

#33. What is the role of in the treatment of middle cerebral artery ...

HMG-CoA reductase inhibitors, or statins, have been shown to decrease the 10-year ... Statin potency from lowest to highest based on the maximum dose is ...

#34. Statin Potency, LDL Receptors and New Onset Diabetes

Editorial: Statin Potency, LDL Receptors and New Onset Diabetes. Author(s): Vasilios G. Athyros, Niki Katsiki, Asterios Karagiannis, ...

#35. Statin potency and the risk of hospitalization for ... - ReadCube

A total of 217 721 patients entered the cohort on a lower potency statin and ... Higher potency statins were not associated with a decreased risk of HCAP ...

#36. Use of High-potency Statins After Percutaneous ...

Use of High-potency Statins After Percutaneous Revascularization. Uso de estatinas de alta potencia tras revascularización percutánea.

#37. Statins in older adults

Diabetes has also been found to be more common in older patients and those taking higher dose and higher potency statins.14. Studies have reported reversible ...

#38. Important safety label changes to cholesterol-lowering statin ...

The statin drug labels have been revised to provide patients with more information on the ... unrelated to potency or to individual statin.

#39. Statin Potency and Hospitalization Risk - Infectious Disease ...

Study finds an increased hospitalization risk for community-acquired pneumonia with higher-potency vs lower-potency statins.

#40. Use of Statins in an Australian Elderly Population - ClinMed ...

High potency/high dose statin use was higher among secondary prevention patients than among primary prevention patients (aOR=1.88, 1.81-1.95). Conclusion: ...

#41. High Potency Statins and the Risk of Diabetes - Full Text View

Statins are a class of cholesterol lowering medications that are prescribed for the prevention and treatment of cardiovascular disease.

#42. Statins: Common questions answered - Heart Matters magazine

Statins are drugs that lower your body's cholesterol level reducing your risk of heart and circulatory disease. Read FAQs like side effects and safety.

#43. 使用高效能史達丁但不是所有史達丁能降地新生骨質疏鬆性骨折 ...

英文：High-potency statins but not all statins decrease the risk of ... 以追蹤世代研究方法瞭解台灣人服用不同種類降血脂statin產生骨質疏鬆性 ...

#44. Statins as Potential Antimalarial Drugs: Low Relative Potency ...

Both statins showed antimalarial activity, but atorvastatin was more potent than rosuvastatin. The IC50 and IC90 values for each statin did not ...

#45. Statin potency and the risk of hospitalization for community ...

Statin potency and the risk of hospitalization for community-acquired pneumonia. Publication Type: Journal Article. Authors: Shin, J. Y.; Eberg, M.; Ernst, ...

#46. Simplified lipid guidelines - The College of Family Physicians ...

Low-potency statin use increases the risk of developing type 2 diabetes by approximately 1 in 250 over 5 years.36. High-potency (over low-potency) statins might ...

#47. Ezetimibe Added to Statin Therapy after Acute Coronary ...

Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but whether the addition of ...

#48. [護理新知] 大劑量高效statin類藥物可降低失智風險（High-dose ...

專家指出，上述結果為破解statin類藥物與失智症難題提供了新的訊息， ... 可降低失智風險（High-dose, high-potency statins reduced dementia risk） ...

#49. and high-potency statins in people at low cardiovascular risk

compared low-potency statins (fluvastatin, lovastatin, prava statin and simvastatin) and high-potency statins (atorva statin and rosu-.

#50. 2018 Guideline on the Management of Blood Cholesterol

level ≥190 mg/dL [≥4.9 mmol/L]), without calculating 10-year. ASCVD risk, begin high-intensity statin therapy. “Top Ten Messages” is continued in the next ...

#51. Association between Use of Statin and Risk of Dementia

High potency statin was significantly associated with a decreased risk of dementia risk (RR 0.68, 95% CI 0.54–0.86, p < 0.001), while low ...

#52. Statin 類藥物相關的肌肉症狀／楊璦瑜、郭震羣 - 藥學雜誌電子 ...

Davidson MH,Dillon MA, Gordon B, et al: Colesevelam hydrochloride (cholestagel): a new, potent bile acid sequestrant associated with a low ...

#53. Statin potency and the risk of hospitalization for ... - Europe PMC

Higher potency statins were not associated with a decreased risk of HCAP compared with lower potency statins. Keywords: community‐acquired pneumonia, ...

#54. Projected Cost-Effectiveness of Ezetimibe/Simvastatin ...

the INFORCE study, 384 patients taking statins at stable doses for. 6 weeks before hospital admission were stratified by statin dose/potency.

#55. HMG-CoA Reductase Inhibitors Topic Review | Learn the Heart

Also known as statins, HMG-CoA reductase inhibitors work by inhibiting the synthesis of ... Newest statin; Moderate potency; Few drug interactions.

#56. Vitamin D deficiency reduces statin potency, increases risk of ...

Statins are widely prescribed to reduce LDL cholesterol levels and so reduce the risk of cardiovascular disease. Raised levels of LDL ...

#57. Muscle-Related Statin Effects Seem to Correlate With Potency

The rates of muscle-related adverse effects (AEs) differ greatly for various statins, with the highest reported rates seen for rosuvastatin.

#58. Relationship Between Dosage and Potency of Statins With ...

The revolutionary results of statin in the prevention and therapy of cardiovascular diseases achieved that the target values of LDL cholesterol ...

#59. Cardio protective drugs: Statins & more - European Society of ...

Statins & more. Overview of common lipid-lowering drugs used in secondary prevention to reach LDL treatment goals. 30 Jun 2017. Krychtiuk, MD, PhD.

#60. Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in ...

As a result, seven statin monotherapy treatments in 50 studies (51956 ... and atorvastatin are traditionally high-potency statins, ...

#61. Statin Medications: Drugs for Improving Cholesterol Levels

Certain statins are more potent, meaning they reduce your LDL and total cholesterol levels more than other statins. Some statins have been shown to reduce the ...

#62. What You Should Expect From Statin Therapy - Cleveland ...

Although statins all belong to the same drug class, they differ in how potent they are and how much they can lower LDL cholesterol.

#63. Statin generics: no differences in efficacy after switching

More importantly, the two active substances are not of equal potency: atorvastatin is more potent than the same molar quantity of simvastatin [3]. The dose ...

#64. HMG-CoA Reductase Inhibitors (Statins) - Gov.bc.ca

3 Characteristics of Various Statins. ... Switch the patient to the fully covered statin at a ... Approximate Potency (% LDL lowering)3. • Atorvastatin.

#65. Statin potency associated with incident diabetes - ProQuest

Statin potency associated with incident diabetes in a real-world evaluation. Steen, Dylan L; Bhatt, Deepak L. Evidence - Based Medicine; London Vol.

#66. Crestor vs. Lipitor: Differences, similarities, and which is better ...

Your doctor may have also mention starting a statin medication. Statins are popular prescription medications, also known as HMG-CoA reductase inhibitors.

#67. Major Recommendations for Statin Therapy for Atherosclerotic ...

Moderate Intensity Statin Dosing. High-Intensity Statins. • Atorvastatin 40-80 mg. • Rosuvastatin 20-40 mg. Moderate-Intensity Statins.

#68. Statin Therapy in Children | IntechOpen

Statins are one of the most potent classes of lipid lowering medications for CV risk reduction. This chapter describes the current screening and management ...

#69. What role does statin potency play in diabetes development? - PCDS

What role does statin potency play in diabetes development? Resource topics: Cardiovascular disease. Date: 13 October 2014. Author(s): Jiten Vora ...

#70. Topic 36: Statins: keeping the benefits, reducing the risks

If your patient is taking a high dose or high potency statin, consider: the anticipated clinical benefit against the increased risk of myopathy lowering the ...

#71. Statin Potency and Properties of Different Statins - GrepMed

Statin Potency and Properties of Different Statins • High Intensity - atorvastatin 40-80mg, rosuvastatin 20-40mg • Moderate Intensity ...

#72. Perioperative statin therapy in patients at high risk for ...

Statins differ in their lipophilicity, half-life, and potency, which give them different potencies for extra-hepatic HMG-CoA reductase ...

#73. HEALTH: Statin potency tracks muscle problems, study finds

Crestor, the most potent statin, topped the list with the most frequent muscle problems, the study found. It's known generically as rosuvastatin ...

#74. Less Than Half of ACS Patients Are Prescribed High-Potency ...

With patients unlikely to switch from a low- to high-potency statin, starting guideline-recommended therapy in hospital is critical, ...

#75. Statin therapy and reductions in low-density lipoprotein ...

The utility of statins with increased potency in reducing low-density lipoprotein cholesterol (LDL-C) is indicated by evidence that aggressive LDL-C ...

#76. Rosuvastatin: a highly potent statin for the prevention and ...

Since the identification of a fungal metabolite that inhibits HMG-CoA reductase in 1976, statins have emerged rapidly as the global leader ...

#77. Statin potency and the risk of hospitalization for community ...

Higher potency statins were not associated with a decreased risk of HCAP compared with lower potency statin, and high-dimensional propensity scores were ...

#78. High-Potency Statins Associated with Acute Kidney Injury

Overall, 33% received high-potency statins. During the first 120 days of treatment, 4700 patients without chronic kidney disease (CKD) and 1900 ...

#79. Statin Utilization - Magellan Rx Management

Discontinuations Among Statin Users in a ... statin potencies, statin intolerance, and discontinuations. • Potency was defined based on the ATP-IV.

#80. Statins - Knowledge @ AMBOSS

Statins are the lipid-lowering drugs of choice. ... potency. increases in the following order: Fluvastatin → Lovastatin → Pravastatin ...

#81. Statin potency and the risk of hospitalization for community ... - Scite

Mentioning: 6 - Higher potency statins were not associated with a decreased risk of HCAP compared with lower potency statins.

#82. Editorial: Statin Potency, LDL Receptors and New Onset Diabetes ...

Editorial: Statin Potency, LDL Receptors and New Onset Diabetes. Author(s): Vasilios Athyros , Niki Katsiki , Asterios Karagiannis , Dimitri Mikhailidis.

#83. Combination Therapy Versus Intensification of Statin ...

Moderate SOE from three trials found that low-potency statin with niacin raises HDL-c up to 27 percent more than mid-potency statin monotherapy.

#84. Statin potency and the risk of hospitalization for ... - CAB Direct

Aim: Previous studies suggest that statins may have beneficial respiratory effects. However, it is unclear if these purported benefits vary with statin ...

#85. Complementary effects ezetimibe on potent statins - PACE-CME

Effects of ezetimibe added to statin therapy on markers of cholesterol absorption and synthesis and LDL-C lowering in hyperlipidemic ...

#86. Pharmacy Integration Insights Issue No 4 - Coordinated Care

Not all statins are created equal and differences in their lipophilicity, potency and pharmacokinetic parameters can impact patient response.

#87. Therapeutic practice patterns related to statin potency and ezetimibe ...

Therapeutic practice patterns related to statin potency and ezetimibe/simvastatin c… more. Peter P. Toth, JoAnne M. Foody, Joanne E. Tomassini, ...

#88. High-potency statins increase hospitalization for community ...

Study finds an increased hospitalization risk for community-acquired pneumonia with higher-potency vs lower-potency statins.

#89. Practical Approach to Managing Dyslipidemia: Role of Statins

Depending on dose used and specific statin, LDL cholesterol reduction of 18% to 55% can be expected. Atorvastatin and rosuvastatin are the most potent statins ...

#90. How Safe Are High-Potency Statins? - Clinical Correlations

The current guidelines now recommend high-dose statins (atorvastatin 40-80 or rosuvastatin 20-40 mg daily) for those with clinical evidence of ...

#91. Explaining statin inhibition effectiveness of HMG-CoA ...

Assuming a correlation between statin potency and the strength of the total HMGR –statin binding energy, clinical data as well as IC50 values of these ...

#92. A List of Statins – Dosing Range and Potency

The single best solution for statin side effects. Click to Order. A List of Statins – Dosing Range and Potency. A list ...

#93. Myopathy with Statins: Check CK Levels and Interactions

The risk is also increased when simvastatin and atorvastatin (both CYP 3A4 substrates; fluvastatin and pravastatin are not) are used concomitantly with potent ...

#94. High-Potency Statins and Acute Kidney Injury–Associated ...

High- versus low-potency statin use was associated with a significant increase in hospitalizations for AKI; the adjusted rate ratio was greatest ...

#95. STATIN USE AND DOSE BY LOW-DENSITY LIPOPROTEIN ... - JACC

To better understand unmet medical needs, we describe statin use by potency across baseline LDL-C category following the occurrence of a CVD event.

#96. Statin potency is associated with risk of new-onset diabetes in ... - Gale

Patients treated with higher potency statins for secondary prevention of cardiovascular disease (CVD) have an increased risk of diabetes compared with ...

#97. Pharmacology 101: An Overview of Statins - tl;dr pharmacy

Relative Statin Potency · Rosuvastatin (Crestor) · Atorvastatin (Lipitor) · Simvastatin (Zocor) · Lovastatin (Mevacor) · Pravastatin (Pravachol).

#98. FDA, Statin and Transplantation - A conundrum - Renal Fellow ...

Rosuvastatin, a novel potent statin, could also be the agent of choice since it is not metabolized by cytochrome P450, though preliminary ...