[減脂期的有機污染物(POPs)危害⚠️]
今天唸到2020年《Food and Chemical Toxicology》期刊關於益生元在減重老鼠身上,是否能降低POP的危害的研究。
所謂「持久性有機污染物(persistent organic pollutants,POP)」,就是像殺蟲劑、塑化劑或是戴奧辛這類的環境荷爾蒙,無法自然分解, #溶於脂肪中,在脂肪組織中的堆積隨著時間而增加,半衰期可達10-15年,對身體造成持續性的破壞,例如心血管疾病、代謝疾病、生殖系統問題甚至是癌症。
一般環境荷爾蒙的暴露分成兩種:
⚠️外源性暴露:
透過污染的食物,例如:魚,尤其是生物鏈當中上層者,或是高脂肪的肉類或內臟。
⚠️內源性曝露:
主要是發生在減肥中,就像我影片中提到 #多喝水的理由之一,就是因為所有脂溶性污染物都會在脂肪分解過程中,從脂肪庫釋放到血液中,若不儘快喝水尿尿排出,對於身體的危害便會上升。
這些環境荷爾蒙的危害,都已在許多減重相關研究(生活型態或減重手術)中被證實,這些減肥後的肥胖受試者的血液中危害物濃度大大提升。
而一個很有趣的觀點就是:
#吃到環境荷爾蒙會容易變胖 這件事,或許跟 #身體的保護機制有關,就像我常提到脂肪的上升是高脂高糖食物造成內毒素上升、身體發炎上升後,免疫對抗發炎後的結果,而當攝入的脂溶性毒素越多,體內的「脂肪庫存拉大」(fat mass storage capacity)這個動作,是為了保護身體,免受毒性傷害的結果。
(亦即不讓脂肪儲存這些脂溶性毒素,而放任在血液中亂跑的話,會有更大的傷害)
#因此減脂本身就承擔著釋放出毒物的過程
#那要如何降低傷害呢?
這個研究用的方式,是介入含植物來源的多酚類的食物,例如:蔓越莓萃取物、菊苣纖維(inulin)、木質素(Lignin),豆類食物也有這些纖維和植物多酚,發現能夠有效降低減脂期老鼠體內的環境荷爾蒙濃度跟傷害。
環境荷爾蒙無所不在,脂肪越多的人「毒倉庫」越大,但是在減脂的過程中總有重複暴露的風險,故建議在減脂中的人除了要 #多喝水,也建議 #多攝取植物性來源的多酚類食物喔!
#今日讀書心得
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