The TAP1 gene provides instructions for making a protein that plays an important role in the immune system. The TAP1 protein assembles with ... ... <看更多>
「tap1 mutation」的推薦目錄：
tap1 mutation 在 TAP1 - Wikipedia 的相關結果
Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. See alsoEdit · ATP-binding ... ... <看更多>
tap1 mutation 在 TAP1 Gene - GeneCards | TAP1 Protein | TAP1 Antibody 的相關結果
Complete information for TAP1 gene (Protein Coding), Transporter 1 ... Mutations in this gene may be associated with ankylosing spondylitis, ... ... <看更多>
tap1 mutation 在 TAP1 - an overview | ScienceDirect Topics 的相關結果
TAP1 and TAP2 are subunits of a peptide transporter system that carries antigenic peptides to the lumen of the endoplasmic reticulum, where they associate with ... ... <看更多>
tap1 mutation 在 TAP1 mutant mice are deficient in antigen presentation ... 的相關結果
TAP1 -deficient mice are defective in the stable assembly and intracellular transport of class I molecules and consequently show severely reduced levels of ... ... <看更多>
tap1 mutation 在 TAP1 Gene - Somatic Mutations in Cancer - COSMIC 的相關結果
TAP1 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, TAP1 Genome Browser, TAP1 References. ... <看更多>
tap1 mutation 在 TAP1 Gene | Encyclopedia MDPI 的相關結果
At least six mutations in the TAP1 gene have been found to cause bare lymphocyte syndrome type I (BLS I). This immune system disorder often causes recurrent ... ... <看更多>
tap1 mutation 在 TAP1 - Antigen peptide transporter 1 - Homo sapiens (Human) 的相關結果
Peptide antigen binding to ATP-loaded TAP1-TAP2 induces a switch to ... Features. Showing features for natural variant, mutagenesis. ... <看更多>
tap1 mutation 在 002458 - TAP1- Strain Details - The Jackson Laboratory 的相關結果
Mice homozygous mice for the Tap1tm1Arp targeted mutation are viable and fertile. They are defective in the stable assembly and intracellular transport of ... ... <看更多>
tap1 mutation 在 TAP1 protein expression summary 的相關結果
Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. ... <看更多>
tap1 mutation 在 A novel mutation in TAP1 gene leading to MHC ... - Europe PMC 的相關結果
Abstract. Major histocompatibility complex (MHC) class I deficiency syndrome is a rare primary immunodeficiency caused by mutations in the peptide transporter ... ... <看更多>
tap1 mutation 在 A novel mutation in TAP1 gene leading to ... - ResearchGate 的相關結果
Mutations of the TAP1 gene severely alter antigen presentation and are associated with immune-insufficiency (Hanalioglu et al. 2017 ). More subtle variations in ... ... <看更多>
tap1 mutation 在 TAP1 Gene 的相關結果
cell lines with TAP1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. CTD Gene-Chemical Interactions, chemicals interacting with TAP1 ... ... <看更多>
tap1 mutation 在 Transporter associated with antigen processing 1 (TAP1 ... 的相關結果
Transporter associated with antigen processing 1 (TAP1) is a transporter protein that represent tumor antigen in the MHC I or HLA complex. Any ... ... <看更多>
tap1 mutation 在 Walker A Lysine Mutations of TAP1 and TAP2 Interfere with ... 的相關結果
Mutants TAP1(K544M) and. TAP2(K509M) were expressed in insect cells, and the effects of the mutations on nucleotide binding, peptide binding, and peptide ... ... <看更多>
tap1 mutation 在 Mouse strains with point mutations in TAP1 and TAP2 的相關結果
The mutation does not affect mRNA levels, but results in a very severe reduction in TAP2 protein. TAP1 protein levels are also decreased in ... ... <看更多>
tap1 mutation 在 Interferon Induction of TAP1 | Circulation Research 的相關結果
In HeLa cells, mutation of the ISRE abolishes the IFN-α/β response, ... TAP1 promoter-reporter constructs containing a mutant ISRE and a wild-type or mutant ... ... <看更多>
tap1 mutation 在 Splice acceptor site mutation of the transporter associated with ... 的相關結果
(GenBank accession numbers: TAP1*0102N cDNA sequence, AB012644; TAP1*0102N genomic sequence, AB012645.) TAP, transporter associated with antigen processing. It ... ... <看更多>
tap1 mutation 在 TAP1, a potential immune-related prognosis biomarker with ... 的相關結果
TAP1 is an immunomodulation-related protein that plays different roles in various malignancies. This study investigated the transcriptional ... ... <看更多>
tap1 mutation 在 Reduced expression of Tap1 and Lmp2 antigen-processing ... 的相關結果
A mutation (T-->A) has now been detected in the shared bidirectional promoter of the Lmp2 and Tap1 genes in the nonobese diabetic (NOD) mouse. ... <看更多>
tap1 mutation 在 A TAP1 null mutation leads to an enlarged olfactory bulb and ... 的相關結果
A TAP1 null mutation leads to an enlarged olfactory bulb and supernumerary, ectopic olfactory glomeruli [2013]. Ernesto Salcedo; Nicole M. Cruz; Xuan Ly; ... ... <看更多>
tap1 mutation 在 TAP1 | Cancer Genetics Web - CancerIndex 的相關結果
Gene: TAP1; transporter 1, ATP binding cassette subfamily B member ... TAP1 COSMIC, Sanger Institute Somatic mutation information and related details. ... <看更多>
tap1 mutation 在 The mutation in the ATP-binding region of JAK1 ... - Nature 的相關結果
The mutation in the ATP-binding region of JAK1, identified in human uterine leiomyosarcomas, results in defective interferon-γ inducibility of TAP1 and LMP2. T ... ... <看更多>
tap1 mutation 在 Cancer Immune Evasion Through Loss of MHC Class I ... 的相關結果
Loss OF MHC I Expression in Cancers Through Mutation or Deletion of ... Van Kaer L, Ashton-Rickardt PG, Ploegh HL, Tonegawa S. TAP1 mutant mice are ... ... <看更多>
tap1 mutation 在 Mouse strains with point mutations in TAP1 and TAP2 的相關結果
Mouse strains with point mutations in TAP1 and TAP2 ... with a point mutation in the transporter associated with antigen processing (TAP)2; ... ... <看更多>
tap1 mutation 在 Entry - #604571 - BARE LYMPHOCYTE SYNDROME, TYPE I 的相關結果
A number sign (#) is used with this entry because bare lymphocyte syndrome type I can be caused by mutation in the TAP2 (170261), TAP1 (170260), ... ... <看更多>
tap1 mutation 在 Structural determinants of peptide-dependent TAP1-TAP2 ... 的相關結果
cancers and viral immune evasion. But the mechanisms whereby the cancer-derived mutations in. TAP1-TAP2 or viral factors targeting the PLC, ... ... <看更多>
tap1 mutation 在 Structural determinants of peptide-dependent TAP1-TAP2 ... 的相關結果
Structural determinants of peptide-dependent TAP1-TAP2 transit passage targeted by viral proteins and altered by cancer-associated mutations. ... <看更多>
tap1 mutation 在 Structure and Function of TAP, the Transporter Associated ... 的相關結果
mutated proteins. MHC II molecules found only ... derived from non self proteins or mutated self pro- ... transport, whereas the same mutation in TAP1 (site. ... <看更多>
tap1 mutation 在 A TAP1 null mutation leads to an enlarged olfactory ... - Journals 的相關結果
A TAP1 null mutation leads to an enlarged olfactory bulb and supernumerary, ectopic olfactory glomeruli. Ernesto Salcedo, Nicole M. Cruz, Xuan Ly, ... ... <看更多>
tap1 mutation 在 Altered natural killer cell repertoire in Tap-1 mutant mice. - PNAS 的相關結果
Tap-] mutant mice are deficient in peptide transport, and consequently also in normal MHC class I-restricted antigen presentation. Cells from Tap-i. ... <看更多>
tap1 mutation 在 Tap1 | Mus musculus gene - Alliance of Genome Resources 的相關結果
Orthologous to human TAP1 (transporter 1, ATP binding cassette subfamily B member). MGI Description. PHENOTYPE: Mice homozygous for targeted mutations that ... ... <看更多>
tap1 mutation 在 Antigen Peptide Transporter 1 (TAP1) Promotes Resistance to ... 的相關結果
Mitogen-activated protein kinase (MAPK) kinase (MEK) inhibitors show limited benefit in Kirsten rat sarcoma (KRAS) mutant pancreatic cancer due to drug ... ... <看更多>
tap1 mutation 在 MHC Class I Antigen Processing and Presenting Machinery 的相關結果
Both TAP1 and TAP2 contain a hydrophobic transmembrane domain and a cytosolic ... Frameshift mutation in TAP1 gene, TAP2, Melanoma (cell line), 139. ... <看更多>
tap1 mutation 在 Phenotypic Mutation 'rose' - Mutagenetix 的相關結果
The mutated nucleotide is indicated in red lettering, and results in an aspartic acid to valine substitution at amino acid 643 of the TAP1 protein. Illustration ... ... <看更多>
tap1 mutation 在 TAP1base: TAP1 deficiency | Main page | 的相關結果
Short description of the TAP1base : Our other bioinformatics services: SH2base - Database for pathogenic SH2 domain variations ... <看更多>
tap1 mutation 在 Increase in positive selection of CD8+ T cells in TAP1-mutant ... 的相關結果
Mice harboring a deletion of the gene encoding the transporter associated with antigen presentation-1 (TAP1) are impaired in providing major ... ... <看更多>
tap1 mutation 在 A TAP1 null mutation leads to an enlarged olfactory ... - FiNDit 的相關結果
Major histocompatibility class I (MHCI) molecules are well known for their immunological role in mediating tissue graft rejection. ... <看更多>
tap1 mutation 在 Transporter Associated with Antigen Processing 1 (TAP1) as a ... 的相關結果
The copy number alteration and mutation frequency and expression in different cancer studies were analyzed using cBioPortal. ... <看更多>
tap1 mutation 在 TAP1 Polyclonal Antibody (11114-1-AP) 的相關結果
Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. For Research Use Only. Not for ... ... <看更多>
tap1 mutation 在 TAP1 Research Products - Novus Biologicals 的相關結果
Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. ... <看更多>
tap1 mutation 在 Syndrome de déficience en HLA de classe 1 secondaire à ... 的相關結果
Syndrome de déficience en HLA de classe 1 secondaire à une mutation de TAP1 responsable d'une granulomatose chronique associé à des surinfections bronchiques - ... ... <看更多>
tap1 mutation 在 TAP.html - Biology 的相關結果
Cells with a mutation in TAP1 or TAP2 express abnormally low levels of MHC class I molecules on the surface because MHC class I molecules are unstable ... ... <看更多>
tap1 mutation 在 TAP1 - Orphanet 的相關結果
TAP1 - transporter 1, ATP binding cassette subfamily B member ... Mutation germinale causale dans Déficit immunitaire par déficit d'expression des molécules ... ... <看更多>
tap1 mutation 在 HLA class I deficiencies due to mutations in subunit 1 of the ... 的相關結果
The transporter associated with antigen processing (TAP), which is composed of two subunits (TAP1 and TAP2) that have different biochemical and functional ... ... <看更多>
tap1 mutation 在 TAP deficiency syndrome - VisualDx 的相關結果
The TAP complex, a heterodimer consisting of 2 subunits (TAP1 and TAP2) ... Deletion or mutation of the genes encoding either subunit of the ... ... <看更多>
tap1 mutation 在 Tap1 - transporter 1, ATP-binding cassette, sub... - WikiGenes 的相關結果
In this study, we demonstrate that, similar to lymphoma cell lines with mutations in Tap-1 or Tap-2, the reduced expression of class I molecules on the ... ... <看更多>
tap1 mutation 在 Insertional Inactivation of Treponema denticola tap1 Results in ... 的相關結果
Reverse transcriptase PCR revealed that the erythromycin resistance cassette within tap1 did not terminate fla operon transcription in either mutant. Moreover, ... ... <看更多>
tap1 mutation 在 Deducing Multidecadal Anthropogenic Global Warming ... 的相關結果
The mutation in the ATP-binding region of JAK1, identified in human uterine leiomyosarcomas, results in defective interferon-γ inducibility of TAP1 and LMP2. ... <看更多>
tap1 mutation 在 Increase in Positive Selection of CD8 + T Cells in TAPl-Mutant ... 的相關結果
Cell surface expression and intracellular transport of MHC class I molecules in TAP1- BA2 and TAP1- B27 mice. (aft) Flow cytometric analysis of Ly5- splenocytes ... ... <看更多>
tap1 mutation 在 Gene mutation linked to leprosy in Indians - The Hindu 的相關結果
TAP1 gene is one of the several genes that regulate the immune response and its variations were earlier implicated in tuberculosis and auto- ... ... <看更多>
tap1 mutation 在 Homozygous Human TAP Peptide Transporter Mutation in ... 的相關結果
Mutation in HLA Class I Deficiency ... 2A) with polyclonal antibodies to TAP1 and ... probably due to a mutation affecting only the. TAP2 gene. ... <看更多>
tap1 mutation 在 The transporter associated with antigen processing - De Gruyter 的相關結果
Interestingly, a single point mutation of the consensus D-loop aspartate to an alanine in TAP1 abolishes ATP hydrolysis, whereas transport ... ... <看更多>
tap1 mutation 在 Identification of miR-200a-5p targeting the peptide transporter ... 的相關結果
mediated control of the peptide transporter subunit TAP1 in melanoma thereby leading to a ... Mutagenesis kit (NEB) was employed according to manufac-. ... <看更多>
tap1 mutation 在 Associations of genetic variants at TAP1 and TAP2 with ... 的相關結果
porter-associated antigen processing (TAP1) and rs2228396 of TAP2 with ... Consequently, some mutations located within key areas of TAP ... ... <看更多>
tap1 mutation 在 Association of TAP1 Gene Polymorphism in Human Papilloma ... 的相關結果
TAP1I333V polymorphism genotyping was performed by amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) (Figure 1) as described by ... ... <看更多>
tap1 mutation 在 Microsatellite instability derived JAK1 frameshift ... - Oncotarget 的相關結果
Sixty-two (34%) ECs showed microsatellite instability, of which 22 (35%) had a JAK1 mutation. LMP7, TAP1 and HLA class I protein expression ... ... <看更多>
tap1 mutation 在 Case 4: MHC Class I Deficiency - Angelfire 的相關結果
The genes for the TAP1:TAP2 transporter ... 4.4 The TAP1 and TAP2 transporter ... Only one possibility remained to be explored-a mutation in the TAP1 or. ... <看更多>
tap1 mutation 在 Splice acceptor site mutation of the transporter associated with ... 的相關結果
time a splice site mutation in the TAP1 gene of another BLS patient. In addition, class I heavy chains (HCs) did not form the normal complex with tapasin in ... ... <看更多>
tap1 mutation 在 TP53 Mutations Promote Immunogenic Activity in Breast Cancer 的相關結果
TP53 mutations may promote immunogenic activity in BC, suggesting that the ... B2M, HLA-A, and TAP1 (MHC Class I), and GZMA and PRF1 (cytolytic activity) ... ... <看更多>
tap1 mutation 在 MHC Deficiency - Immunology - Medbullets Step 1 的相關結果
Further genetic testing shows the infant has a mutation in the tapasin protein. ... transporting the antigen peptide (TAP 1 and 2) into the ... ... <看更多>
tap1 mutation 在 Microsatellite instability derived JAK1 frameshift mutations are ... 的相關結果
TAP1 expression and presence of CD8-positive T-cells were not related to JAK1 mutations. In 198 additional microsatellite unstable ECs, the JAK1 mutation ... ... <看更多>
tap1 mutation 在 Molecular Characterization of the Plastid-localized ABC ... 的相關結果
AtTAP1 to six TAP1 proteins of other plant species .... 49 ... showed that the TAP1 cDNA was absent in the mutant line (M1) but present in WT. ... <看更多>
tap1 mutation 在 Animal Biotechnology - Taylor & Francis Online 的相關結果
The expression of TAP1 candidate gene, but not its polymorphism and ... based on an APC 1311 mutation (orthologous to human APC 1309 ). ... <看更多>
tap1 mutation 在 p53, cancer and the immune response | Journal of Cell Science 的相關結果
Loss or mutation of p53 in cancers can affect the recruitment and ... presentation through transcriptional control of ERAP1 and TAP1. ... <看更多>
tap1 mutation 在 JAK1 truncating mutations in gynecologic cancer define new ... 的相關結果
Cancer-associated protein tyrosine kinase (PTK) mutations usually are ... stimulated LMP2 and TAP1-promoter activities in JAK1 mutation cell. ... <看更多>
tap1 mutation 在 Structure of the transporter associated with antigen processing ... 的相關結果
In addition, both TAP1 and TAP2 contain an N-terminal transmembrane ... where each of the first 35 residues on ICP47 were mutated to alanine ... ... <看更多>
tap1 mutation 在 G gene polymorphisms with latent tuberculosis infections in ... 的相關結果
TAP1 mutant mice are deficient in antigen presentation, surface class-I molecules, and CD4-8 + T cells. Cell. 1992;71:1205-14. 18. Palomares-Marin J, Govea- ... ... <看更多>
tap1 mutation 在 MHC Class I Deficiency - Immunodeficiency Search 的相關結果
TAP 1 or TAP 2 Deficiency - Homozygous mutations in TAP 1 and TAP 2 have been ... Tapasin Deficiency - One patient with Tapasin mutation has been reported. ... <看更多>
tap1 mutation 在 Microsatellite instability derived JAK1 frameshift mutations are ... 的相關結果
TAP1 expression and presence of CD8-positive T-cells were not related to JAK1 mutations. In 198 additional microsatellite unstable ECs, the JAK1 mutation ... ... <看更多>
tap1 mutation 在 (PDF) A TAP1 Null Mutation Leads to an Enlarged Olfactory 的相關結果
A TAP1 Null Mutation Leads to an Enlarged Olfactory Bulb and Supernumerary, Ectopic Olfactory Glomeruli by Ernesto Salcedo, Nicole M. Cruz, Xuan Ly, ... <看更多>
tap1 mutation 在 Variant Detail : MGeND 的相關結果
<0.001, vitiligo, Transporter TAP1-637G and immunoproteasome PSMB9-60H variants influence the risk. ... Type, Amino Mutation, Transcript Position, Links ... ... <看更多>
tap1 mutation 在 TAP1 | definition of TAP1 by Medical dictionary 的相關結果
TAP1 pumps degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment. Molecular pathology. TAP1 mutations have been ... ... <看更多>
tap1 mutation 在 Oblikacky y barbie - PMI 的相關結果
... Phim chien than lu bo tap 1 Old age homes in israel Dev c++ download win xp ... Ncx1 mutation Common guitar chord shapes George clooney paradiso amaro ... ... <看更多>
tap1 mutation 在 Dr Evil Quotes Meme Generator - 4A Safety 的相關結果
Evil. synonymous mutation vs nonsynonymous mutation x why do i like the smell of my ... It is on our list, but we don't "have it on tap" 1 Off the wall. ... <看更多>
tap1 mutation 在 High Risk Hpv Can Lead To Quizlet 的相關結果
High-risk HPV genome integration may lead to deletion and/or mutation of both host and viral genes ... leading to repression of MHC I, LMP2, and TAP1 gene. ... <看更多>
tap1 mutation 在 Encyclopedia of Immunobiology - 第 286 頁 - Google 圖書結果 的相關結果
(2010) TAP1 Melanoma Insertion Anecdotical Seliger et al. (2001) TAP1 Lung Mutation 1 Chen et al. (1996) TAP1 Kidney Indels and mutations 0 Seliger et al. ... <看更多>
tap1 mutation 在 Primary Immunodeficiency Diseases: Definition, Diagnosis, ... 的相關結果
Homozygous TAP1 and TAP2 mutations have been found in seven and five families respectively [88, 91, 146, 261, 274, 446]. All theses mutations lead a ... ... <看更多>
tap1 mutation 在 Issues in Life Sciences: Cellular Biology: 2011 Edition - Google 圖書結果 的相關結果
... Canberra: Mouse strains with point mutations in TAP1 and TAP2 Scientists discuss in ... with a point mutation in the transporter associated with antigen ... ... <看更多>
tap1 mutation 在 Stem Cells and Their Potential for Clinical Application 的相關結果
In particular mutations, deletions, rearrangement and/or loss of ... In addition, one melanoma cell line exhibiting a TAP1 mutation also had a mutation in ... ... <看更多>
tap1 mutation 在 Recent Advances in Flowering Time Control 的相關結果
The loss of PHYB in the phyB msi1-tap1 double mutant led to flowering with 15 rosette leaves (RL) in LD, which was intermediate between the phyB single ... ... <看更多>
tap1 mutation 在 Mechanisms of Tumor Escape from the Immune Response 的相關結果
However , no TAP1 or TAP2 gene mutations have yet been described in melanoma cells . To the best of our knowledge , a TAP1 mutation has been identified only ... ... <看更多>
tap1 mutation 在 Progress in Basic and Clinical Immunology - 第 81 頁 - Google 圖書結果 的相關結果
Therefore, either reduced nucleotide hydrolysis by TAP1 is sufficient to eliminate class I expression by non-lymphoid cells, or the Walker B mutation ... ... <看更多>
tap1 mutation 在 2023 Gene knockout 방법 - monaliqsa.online 的相關結果
The high frequency with which CRISPR-induced mutations can … Gene knockdown methods temporarily stop or decrease the expression of one or more targeted ... ... <看更多>
tap1 mutation 在 Mummified monk in statue - ZAB.RU 的相關結果
Floss urban dictionary Barylskiy Ca map ma tap 1 Zapalniczki honest. ... to praise and thank allah Monoallelic mutation analysis Impulsive sentence Integro ... ... <看更多>
tap1 mutation 在 Make Money as a TaskRabbit Tasker Here s How It Works 2023 的相關結果
... on Multicenter Team Linking Gene Mutation to Crohn s Disease ... Tieng Viet Lop 1 Tap 1 APK Download for Android · Forgot the keys? ... <看更多>
tap1 mutation 在 What Is Nummular Eczema? Symptoms Causes Diagnosis ... 的相關結果
This is because of genetic mutations among certain ethnic groups that compromise the skin barrier, per the NEA. The appearance of eczema can ... ... <看更多>
tap1 mutation 在 A novel mutation in TAP1 gene leading to MHC class I ... 的相關結果
A novel mutation in TAP1 gene leading to MHC class I deficiency: Report of two cases and review of the literature. Clin Immunol. 2017 May;178:74-78. doi: ... ... <看更多>