關於 gnrh antagonist ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. Flexible Low-Dose GnRH Antagonist Protocol Is Effective in ...

Gonadotropin-releasing hormone antagonist (GnRH-ant) has been shown to negatively influence endometrial receptivity. Reducing the GnRH-ant ...

#12. GnRH antagonists - Fertility and Sterility

GnRH antagonists, which have recently been introduced, may offer advantages over GnRH agonists. The GnRH antagonists bind to gonadotrope GnRH receptors and ...

#13. List of Gonadotropin-releasing hormone antagonists - Drugs ...

*Gonadotropin-releasing hormone (GnRH) antagonists are synthetic analogs of gonadotropin-releasing hormone, which is produced by the hypothalamus and ...

#14. GnRH agonist 與GnRH antagonist在卵巢顆粒細胞內的不同 ...

目前知道GnRH agonist是經由造成腦下垂體 desensitization 和GnRH receptor down-regulation而達到抑制性腺刺激素. (gonadotropin)分泌的目的。GnRH antagonist則是和 ...

#15. Effectiveness of GnRH Antagonist in the Management ... - PLOS

Background Recent studies have indicated the use of gonadotropin-releasing hormone antagonists (GnRH-ant) as an adjuvant treatment to ...

#16. Gonadotrophin-releasing hormone antagonists versus GnRH ...

Gonadotrophin-releasing hormone (GnRH) antagonists are now being seriously considered as a potential means of achieving better treatment ...

#17. A Flexible Multidose GnRH Antagonist versus a Microdose ...

Objective. To compare the effectiveness of a flexible multidose gonadotropin-releasing hormone (GnRH) antagonist against the effectiveness of a microdose ...

#18. New 0ral Gonadotropin-Releasing Hormone (GnRH) Antagonist

A new oral nonpeptide GnRH antagonist, relugolix, promptly lowers pituitary gonadotropin by GnRH receptor competition lowering estrogen ...

#19. Ultrashort GnRH Agonist/Antagonist Versus ... - Clinical Trials

The ultrashort flare GnRH agonist combined with flexible multidose GnRH antagonist protocol during COH cycle resulted in a significantly higher clinical ...

#20. 腦下垂體抑制劑(GnRH agonist及GnRH antagonist ) - 黃建榮婦 ...

腦下垂體抑制劑(GnRH agonist及GnRH antagonist ). 八月17 日, 2018; Category: 常見藥物介紹. 單獨使用排卵藥時，有一部份患者會發生提早排卵而取不到卵或造成卵子 ...

#21. Overview of GnRH Antagonists Used in IVF Treatments

Learn about the side effects and risks of GnRH antagonists in IVF like Antagon, Ganirelix, Orgalutran, or Cetrotide.

#22. Bruk av GnRH-antagonist ved in vitro-fertilisering - Tidsskrift ...

Anvendelse av GnRH-antagonist er en alternativ behandlingsstrategi for å hindre prematur eggløsning. Denne strategien medfører ikke et lavt ...

#23. An Oral Gonadotropin-Releasing Hormone Antagonist for ...

To compare the efficacy and safety of an oral GnRH antagonist (relugolix) with that of an LHRH agonist (leuprolide) in this setting, ...

#24. GnRH Antagonists Versus GnRH Agonists - YouTube

... data from the phase III PRONOUNCE trial, looking at adverse cardiovascular events associated with GnRH antagonists versus GnRH agonists.

#25. Oral GnRH Antagonist Therapy for mCSPC - OncLive

Implications of treating patients with metastatic castration-sensitive prostate cancer with relugolix, an oral GnRH antagonist.

#26. A Case of Switching from GnRH Agonist to Antagonist for ...

GnRH antagonist and GnRH agonist are widely used as androgen deprivation therapy for metastatic prostate cancer. A previous report demonstrated that ...

#27. Random-start GnRH antagonist for emergency fertility ...

The use of gonadotropin-releasing hormone (GnRH) antagonists has emerged as a convenient strategy to reduce the duration of the treatment cycle.

#28. Hot Line - Do GnRH antagonists have better CV safety than ...

Hot Line - Do GnRH antagonists have better CV safety than GnRH agonists for prostate cancer? 30 Aug 2021. The use of androgen deprivation therapy for the ...

#29. Oral GnRH antagonists could have potential in female ...

Relugolix is a once-daily, oral, gonadotropin-releasing hormone (GnRH) receptor antagonist. There are multiple companies competing in the space, ...

#30. GNRH agonists vs antagonists in prostate cancer - Urology ...

GNRH antagonists act via direct competitive inhibition of the GNRH receptor, thereby blocking its downstream signaling and leading to a rapid ...

#31. Gonadotropin-Releasing Hormone Antagonists in Prostate ...

The oral GnRH antagonist relugolix, also known as TAK-385, is currently being evaluated as a potential treatment for prostate cancer. The ...

#32. New considerations for ADT in advanced prostate cancer and ...

GnRH antagonists achieve castration faster than agonists and may offer ... The third-generation GnRH antagonist degarelix was synthetically ...

#33. Coupling State of the Type I GnRH Receptor - Cancer Research

Gonadotropin-Releasing Hormone (GnRH) Antagonists Promote Proapoptotic Signaling in Peripheral Reproductive Tumor Cells by Activating a Gαi-Coupling State ...

#34. An Oral GnRH Antagonist for Endometriosis Pain - The ...

The FDA has approved elagolix (Orilissa – AbbVie), an oral gonadotropin-releasing hormone (GnRH) antagonist, for management of moderate to ...

#35. GnRH Antagonists: A New Generation of Long Acting ...

A series of antagonists of gonadotropin-releasing hormone (GnRH) of the general formula ...

#36. 改善不孕症婦女治療經驗的新療程:GnRH antagonist輔助療程

傳統的GnRH agonist長療程往往需皮下注射藥物長達兩到三星期的時間，從前一次週期的最後幾天就要開始打針，反之，GnRH antagonist的療程只需要5到7天的皮下注射藥物，就 ...

#37. ORILISSA® (elagolix) Mechanism of Action (MOA)

ORILISSA is a GnRH antagonist that competes with endogenous gonadotropin-releasing hormone (GnRH) for GnRH receptor occupancy and blocks receptors upon ...

#38. GnRH antagonist protects ovarian function - The Lancet

Gonadotropin-releasing hormone (GnRH) antagonists could protect ovarian function in women undergoing chemotherapy, without causing adverse ...

#39. GnRH antagonists - European Journal of Obstetrics and ...

Ovarian stimulation is an important step in the success rate of in vitro fertilization (IVF) allowing multiple follicular growth, several oocytes.

#40. Effects of GnRH Antagonists vs Agonists in Domestic ...

Contents Gonadotrophin-releasing hormone (GnRH) stimulates the pituitary secretion of both luteinizing and follicle-stimulating hormones, ...

#41. Fertility Basics: GnRH Antagonists for In Vitro Fertilization

Gondadotropin-releasing hormone antagonists (GnRH antagonists) are one type of medication used in fertility treatments—examples include ...

#42. Prostate Cancer Medication: Antineoplastics, GnRH Agonist ...

Agents used include the following: Androgen antagonists. Gonadotropin-releasing hormone (GnRH) agonists. GnRH antagonists. Bisphosphonates. Antifungal agents.

#43. Effect of GnRH-antagonist, mifepristone and letrozole on ...

Can luteolysis-targeted drugs, gonadotrophin-releasing hormone antagonist (GnRH-ant), mifepristone and letrozole, administered separately or ...

#44. Effect of GnRH antagonists on clinical pregnancy rates in ...

The patients were randomised into two groups – patients in group A received rFSH + GnRH antagonist (n = 45), while those in group B received only rFSH (n = 63).

#45. Peptidomimetic GnRH Antagonist AEZS-115 Inhibits the ...

Co-treatment experiments of cancer cells with GnRH antagonist cetrorelix and ... Gonadotropin-releasing hormone (GnRH) antagonists induce an immediate ...

#46. Gonadotropin-releasing hormone antagonists versus standard ...

Gonadotropin-releasing hormone (GnRH) antagonists, such as abarelix or degarelix, are new agents for androgen suppression therapy in advanced prostate cancer.

#47. GnRH Antagonist vs Agonist for Metastatic Prostate Cancer ...

Use of degarelix, a gonadotropin-releasing hormone (GnRH) antagonist, is associated with lower short-term risks for death and cardiovascular ...

#48. GnRH Antagonist Articles - UroToday

Androgen deprivation therapy (ADT) is the standard medical approach to the management of prostate cancer. Patients switched from a GnRH antagonist to a GnRH ...

#49. GnRH antagonist versus depot GnRH agonist protocol in ...

... receptivity and high ovarian reserve. The GnRH antagonist (GnRH-ant) protocol has been widely accepted as a prominent intervention to reduce the risk of...

#50. Determination of the ability of a novel, long-acting ...

Determination of the ability of a novel, long-acting subcutaneous GnRH antagonist, VERU-100, to castrate without a testosterone surge in a ...

#51. GnRH antagonist alters the migration of endometrial epithelial ...

Gonadotropin-releasing hormone antagonist (GnRH-ant) and GnRH agonist (GnRH-a) protocols are the two main clinical protocols for controlled ovarian stimulation ...

#52. GnRH Antagonists with or without Add-Back Therapy - MDPI

To evaluate the effectiveness of a new class of medical drugs, namely oral gonadotropin-releasing hormone (GnRH) antagonists, in the management of ...

#53. Abstract 17016: Cardiovascular Safety Profile of Gonadotropin ...

ADT can be achieved through the use of gonadotrophin releasing (GnRH) hormone agonist or, more recently, GnRH antagonists. The objective of this ...

#54. GnRH agonists and antagonists in prostate cancer - GaBI ...

Keywords: drug selection, GnRH (gonadotropin-releasing hormone) agonists, GnRH antagonists, goserelin, leuprorelin, prostate cancer, SOJA (System of ...

#55. GnRH Antagonist-induced Down-regulation of the mRNA ...

Download Citation | GnRH Antagonist-induced Down-regulation of the mRNA Expression of Pituitary Receptors: Comparisons with GnRH Agonist ...

#56. 248P GnRH antagonist plus bicalutamide might be an ...

248P GnRH antagonist plus bicalutamide might be an effective therapy as initial combined androgen blockade for patients with high grade prostate cancer.

#57. GnRH-Agonist vs GnRH-Antagonist Among Patients With ...

In this phase II randomized study of GnRH antagonists versus GnRH agonists in patients with advanced prostate cancer and pre-existing ...

#58. Pubertal blockers for transgender and gender-diverse youth

When taken regularly, GnRH analogues suppress the body's release of sex hormones, including testosterone and estrogen, during puberty. Sex hormones affect:.

#59. A boon for infertility patients: Ovarian stimulation with GnRH ...

[1] GnRH antagonist protocol produced a comparable ovarian response, embryo development, and pregnancy rates to GnRH agonist regime ...

#60. GnRH antagonists - SlideShare

PROTOCOLS FOR IVF GnRH Antagonist Protocols GnRH Agonist Protocols 225 IU per day (150 IU Europe ) Individualized Dosing of FSH/HMG 250 mg per day ...

#61. GnRH agonist or antagonist co-treatment during ovarian ...

The uptake of the use of GnRH antagonists co-treatment in clini- cal practice of IVF is clearly behind expectations. A medline search (per-.

#62. Understanding and Managing Endometriosis - AbbVie

A GnRH antagonist (or gonadotropin-releasing hormone antagonist) therapy is used ... Other common side effects of GnRH antagonists are: anxiety, menstrual.

#63. Early initiation of GnRH antagonist administration in a flex...

Gonadotropin-releasing hormone (GnRH) antagonist protocol is a popular and patient-friendly regimen for controlled ovarian stimulation (COS) during in vitro ...

#64. PRONOUNCE: CV Safety of GnRH Antagonists vs. GnRH ...

The relative cardiovascular safety of gonadotropin-releasing hormone (GnRH) antagonists compared with GnRH agonists in men with prostate ...

#65. Comparing Cardiovascular Outcomes With Degarelix or ...

Since the early 1980s, androgen deprivation therapy (ADT) with gonadotropin-releasing hormone (GnRH) agonist or antagonist therapies has ...

#66. Gonadotropin-releasing hormone antagonist - wikidoc

Unlike the GnRH agonists, long acting or depot forms of the agent are not currently available, thus GnRH antagonists are not used in the long ...

#67. Applications for GnRH antagonists - Cell Press

This meeting explored therapeutic uses of gonadotropin-releasing hormone (GnRH) antagonists in reproduction and in the treatment of cancer.

#68. Cardiovascular Morbidity in a Randomized Trial Comparing ...

Limited data suggest that GnRH (gonadotropin-releasing hormone) antagonist may be associated with a lower risk of cardiovascular disease than ...

#69. Comparison of long GnRH agonist versus GnRH antagonist ...

However, gonadotropin releasing hormone antagonists. (GnRH-ant) have some advantages in mechanisms of actions over GnRHa. Unlike GnRHa, GnRH-ant act by the ...

#70. Elagolix – GnRH Antagonist - Neurocrine Biosciences

Elagolix – GnRH Antagonist. GnRH is a peptide that stimulates the secretion of the pituitary hormones that are responsible for sex steroid production and ...

#71. GnRH Receptor Antagonists - Endometriosis News

Gonadotropin-releasing hormone (GnRH) receptor antagonists are a class of hormonal treatments that can be used to treat endometriosis.

#72. Elagolix, a Novel, Orally Bioavailable GnRH Antagonist under ...

Among these peptide GnRH antagonists, cetrorelix was evaluated for the treatment of endometriosis-related pain in a clinical trial sponsored by ...

#73. Comparative study between agonist and antagonist protocols ...

GnRH agonist long protocol in patients with polycystic ovary syndrome treated by ICSI. Results. There is a statistically significant difference ...

#74. study protocol for a non-inferiority trial | BMJ Open

With traditional fixed or flexible gonadotropin-releasing hormone (GnRH) antagonist protocols, antagonist administration may further reduce LH activity.

#75. GnRH receptor inhibitors - AdooQ® Bioscience

Ozarelix is a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating ...

#76. Clinical and Experimental Reproductive Medicine

The GnRH antagonist is generally started either on a fixed schedule (i.e., day 6 of stimulation), or on a flexible schedule (i.e., appearance of a follicle ...

#77. GnRH antagonist - The Titi Tudorancea Bulletin

Some GnRH antagonists are used to treat advanced prostate cancer. They are also used to treat certain gynecologic conditions and are being studied in the ...

#78. Point Counterpoint in ADT | Agonists versus Antagonists

GnRH Agonist vs. Antagonist Which One? We're going to look at agonist versus antagonist, which one? I think they're both good drugs. I use them both, ...

#79. GnRH Antagonist in Ovarian Stimulation | Obgyn Key

GnRH antagonists suppress gonadotropin secretion by competing with GnRH for the receptors on the pituitary gonadotroph cell membranes.

#80. Table III from GnRH antagonists in ovarian stimulation for IVF.

Table III. Modifications of the standard GnRH antagonist protocol - "GnRH antagonists in ovarian stimulation for IVF."

#81. GnRH, GnRH Analogs, Gonadotropins and Gonadal Peptides

18 Comparison of GnRH antagonist compounds : primate studies for selection of clinically useful analogs K. Gordon , D. R. Danforth , R. F. Williams and ...

#82. Textbook of Minimal Stimulation IVF - 第 81 頁 - Google 圖書結果

Finally, GnRH antagonists give new hope to patients willing to cryopreserve ... GnRH antagonist protocols are short, simple, with good clinical outcomes and ...

#83. Hormones, Hormone Substitutes, and Hormone ...

Pregnancy and infant outcomes after treatment with GnRH antagonist for IVF are particular causes of concern.” “The purpose of this study was to investigate ...

#84. GnRHa 懷孕率略高於GnRH ... - 謝耀元張其真試管嬰兒中心

Abstract. BACKGROUND: Despite the clinical outcomes of ovarian stimulation with either GnRH-agonist or GnRH-antagonist analogues for in ...

#85. Mode of action | ANTEV

Teverelix trifluoroacetate (Teverelix TFA) is a gonadotrophin-releasing hormone (GnRH) antagonist with a novel formulation. GnRH antagonists rapidly ...

#86. Fertility Medication

GnRH antagonist medication. Ganirelix Acetate Injection or Cetrotide, which acts fast, taken a few days after gonadotropins. The antagonist binds to the ...

#87. Manual of Ovulation Induction & Ovarian Stimulation Protocols

Compared with long GnRH agonist protocol, the GnRH antagonist protocol for controlled ovarian stimulation (COS) has offered a greater benefit in reducing ...

#88. Cumulated Index Medicus

In vitro and in vivo activities of reduced - size antagonists domestic ruminants ... The preliminary results ) hypophysectomized by a GnRH antagonist .

#89. Linzagolix Under Review for Treatment of Uterine Fibroids

Linzagolix is a novel, oral gonadotropin-releasing hormone (GnRH) receptor antagonist. The NDA submission is supported by data from the ...

#90. Obseva Announces U.S. FDA Acceptance of New Drug

Linzagolix has a differentiated profile and if approved, would be the first and only GnRH receptor antagonist with flexible dosing options ...

#91. Nifty finds: Super-fast-acting hormone blockers used in Sweden

GnRH agonists are a class of drugs sometimes used as part of medical transition for trans people in order to block the sex hormones produced ...

#92. Gonadotropin Hormones - News-Medical

GnRH antagonists can also be used to suppress gonadotropin secretion. These agents block the GnRH receptor on the gonadotroph cells.

#93. Antagonist protocol in IVF cycle... - Metro IVF Fertility | Facebook

Antagonist protocol in IVF cycle will have about 7 to 10 days of injections (FSH hormone). A second hormone (GnRH antagonist) given for 4 days ensure all...

#94. GnRH What triggers human puberty is one of the central ...

The effects of kisspeptin on LH can be completely abrogated by the co-administration of a GnRH antagonist, demonstrating that this protein ...

#95. Elagolix for fibroids - German Tutor Miami

Elagolix is a potent, orally bioavailable, non-peptide GnRH antagonist that acts by a competitive block of the GnRH receptor.

#96. Regulatory actions for Nov. 23, 2021 - BioWorld

Obseva SA, of Geneva, Linzagolix, Once-daily, oral GnRH receptor antagonist, Heavy menstrual bleeding associated with uterine fibroids in ...

#97. Translational Science Certificate - UCSD School of Medicine

He contributed to the discovery of the peptidic GnRH antagonist degarelix, launched in 2009 as FIRMAGON, and many other peptidic drug candidates in various ...

#98. Oriahnn - PT. BARUNA INDO NUSA

Keywords: Apr 05, 2021 · Oriahnn (Abbvie), a fixed-dose combination of the gonadotropin-releasing hormone (GnRH) receptor antagonist elagolix, the estrogen ...