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關於 leptin obesity ，我們在網路上蒐集到這些相關的討論、資訊與評價

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在leptin obesity這個產品中，有5篇Facebook貼文，粉絲數超過2,874的網紅跟著營養師一起瘦！，也在其Facebook貼文中提到， 【假日還睡眠債，小心愈睡愈胖！ 睡眠不足，肥胖風險+235%‼】 今天(3/19)是 #世界睡眠日！😴 先等等，不是要讓你大爆睡一整天 世界睡眠日的目的是 #推廣健康睡眠 身處繁忙的世界，大家都亞歷山大 隨便問4個人就有1個人睡不好😩 2021年世界睡眠日的主題是 ✨「規律睡眠，迎向...

leptin obesity 在 跟著營養師一起瘦！ Facebook 的精選貼文

跟著營養師一起瘦！ By 跟著營養師一起瘦！

2021-03-19 19:47:05 有 27 人按讚
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【假日還睡眠債，小心愈睡愈胖！
　睡眠不足，肥胖風險+235%‼】

今天(3/19)是 #世界睡眠日！😴
先等等，不是要讓你大爆睡一整天
世界睡眠日的目的是 #推廣健康睡眠
　　
身處繁忙的世界，大家都亞歷山大
隨便問4個人就有1個人睡不好😩
　　
2021年世界睡眠日的主題是
✨「規律睡眠，迎向健康」✨
Regular Sleep, Healthy Future
　　
　　
👩‍⚕「你知道 #規律睡眠能讓你變瘦 嗎！」
　　
今天是禮拜五，相信有些人
已經打算熬夜然後明天睡到自然醒
　　
平日熬夜早起，睡眠不足😪
假日捨不得睡，睡到中午🌞
想補眠還 #睡眠債，小心愈睡愈胖！
　　　　
✈社交時差 (social jetlag)
指的就是週間和週末的睡眠模式差異
平日與假日好像在不同的時區睡覺：
平日0點睡、6點起床，睡眠中點是3:00
假日3點睡、12點起床，睡眠中點是7:30
🕜社交時差就有整整4.5個小時！😱
　　
📖一項6.5萬人的大數據研究發現
愈常在假日補眠的人，愈容易肥胖！
　　
📖還有研究指出，社交時差愈大
不僅腰圍超標，血糖血脂都會受影響
😵腰圍⬆
😵BMI⬆
😵三酸甘油酯TG⬆
😵胰島素阻抗⬆
　　
　　
👩‍⚕「除了規律睡眠，#睡得飽 也很重要！」
　　
📖芝加哥大學抓來一群年輕人做研究
讓他們分別只睡4小時🆚睡足9小時
　　
研究發現，睡眠不足的人😴😴
👉抑制食慾的 #瘦素 下降18%⬇
👉刺激食慾的 #飢餓素 上升28%⬆
👉食慾增加23%⬆
👉饑餓感增加24%⬆
　　
不只這樣，睡眠不足的人
對於高熱量食物：鹹食、甜點、澱粉
食慾大增！！🍟🍰🍪🍦🥖🍞🍝🍚
　　
對於較健康的蔬果、蛋白質、乳製品
食慾反而沒什麼影響😐😐
....
表示增加的食慾都拿去吃不健康的東西了啊！！
　　
　　
📖根據哥倫比亞大學研究
與睡眠時間7-9小時的人相比
👉睡6小時的人肥胖風險高了27%
👉睡5小時的人肥胖風險高了60%
👉只睡2-4小時的人，肥胖風險高了235%！
各位觀眾！是235%啊！！😱😱
　　
　　
想要減肥
#運動、#飲食、#睡眠 是黃金三角
懶的運動、管不住嘴
至少「睡」我還是蠻再行的😏
　　
所以...今天你打算幾點睡呢？😉
　　
圖：好色龍
　　
Reference:
1. Social jetlag and obesity. Curr Biol. 2012 May 22;22(10):939-43.
2. Social Jetlag, Chronotype, and Cardiometabolic Risk. J Clin Endocrinol Metab. 2015 Dec;100(12):4612-20.
3. Inadequate sleep as a risk factor for obesity: analyses of the NHANES I. Sleep. 2005 Oct;28(10):1289-96.
4. Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med. 2004 Dec 7;141(11):846-50.

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?‍⚕營養師韋含 身為一個營養師，怎麼能不愛吃? 用營養健康的方式，快快樂樂的減重 用天然科學的方式，輕輕鬆鬆的變瘦 ☆減肥瘦身 ★科普營養 ☆保健食品 ★營養生活化
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leptin obesity 在 Facebook 的最讚貼文

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2021-01-18 09:17:20 有 32 人按讚
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Vitamin D seems to help fight off viruses, especially COVID-19.

SUNLIGHT:A number of factors can play a role in vitamin D deficiencies in older adults. Because they spend the majority of their time indoors, older adults get minimal exposure to natural sunlight.

1.In aging adults, vitamin D deficiency is strongly linked to muscle weakness, which can manifest in different ways. In general, seniors tend to feel a heaviness in their legs and have difficulty standing up and climbing stairs.
2.Vitamin D is also necessary for aiding and regulating calcium absorption and keeps bones, muscles and teeth in excellent condition. The combination of weakened muscles and bones caused by low vitamin D levels has been associated with an increased risk of falls and fractures, which can be very dangerous and even fatal for the elderly.
3.Vitamin D is believed to help regulate immune function and the release of neurotransmitters in the brain that influence moods
4.Studies have shown that low vitamin D levels may be associated with mental health disorders like seasonal affective disorder (SAD), schizophrenia and depression. Seniors who feel depressed and tired all the time may actually suffer from vitamin D insufficiency or deficiency.
5.In addition, low vitamin D levels may contribute to cognitive decline and a person’s risk of developing Alzheimer’s disease and other forms of dementia.
6.Weight Gain
Vitamin D appears to play an important role in regulating appetite and body weight as well. Research has shown that lower levels of vitamin D are associated with obesity, whereas increased vitamin D levels have been associated with reductions in body fat.
7.It’s believed that vitamin D controls the levels of leptin in the body—another hormone that inhibits hunger and reduces fat storage.
8.When a senior is deficient in vitamin D, these signals to the brain get disrupted and the body doesn’t know when to stop eating. This can make people overeat and gain weight.
9.Fatigue
Many older adults who are tired all the time may not realize that they could have a nutritional deficiency, so they ignore their symptoms. Low vitamin D levels may also cause widespread pain in areas like the shoulders, pelvis, ribcage and lower back, which can leave a senior feeling drained. Someone who has stiff joints and is constantly feeling fatigued might want to boost their vitamin D intake (especially if they do not go outside much or do not eat many fortified foods).
10.Digestive Issues
Studies have shown that low vitamin D levels may contribute to the development of inflammatory bowel disease (IBD), a condition characterized by chronic inflammation in the digestive tract. IBD is split into two main types: ulcerative colitis and Crohn’s disease. To make matters worse, bowel diseases can interfere with the way the intestines absorb dietary fat. Since vitamin D is a fat-soluble vitamin, GI conditions can cause nutritional deficiencies to worsen even further. #COVID19 #vitaminD #sunlight #oldage

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leptin obesity 在 農民教主碎碎念 Facebook 的最佳貼文

農民教主碎碎念 By 農民教主碎碎念

2018-07-16 16:27:02 有 13 人按讚
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不能胖才是大麻煩

Adipose tissue grows by two mechanisms: hyperplasia (cell number increase) and hypertrophy (cell size increase).

We all have a genetic predisposition to the amount of fat mass that we can safely achieve..Some folks have a very limited ability to recruit new adipose cells to store excess lipids in the subcutaneous adipose tissue. The recruitment of new adipose cells is known as Adipogenesis.

Adipogenesis is the process of cell differentiation by which pre-adipocytes become adipocytes. Once these folks can no longer recruit new adipose cells to store excess lipids during times of over-feeding, their existing adipocytes (fat cells) in their fat mass, their adipocytes grow in cell size and they reach a point where they become hypertrophic.

Their adipocytes (fat cells) become very inflamed, very insulin resistant. They start leaking all kinds of inflammatory markers into the circulation. These adipocytes (fat cells) become so insulin resistant that they can no longer properly regulate the flow of fatty acids and glycerol from storage. There is an excess spill-over of fatty acids to the liver. These excess fatty acids are re-esterfied in the liver to triglycerides. These excess fatty acids and triglycerides cause extreme insulin resistance in the liver. They also cause fatty liver. There is a dramatic rise in circulating triglycerides (lipids). These excess lipids also end up stored in the pancreas and other organs causing lipotoxicity. Welcome to T2 diabetes.

"Lipotoxicity is a metabolic syndrome that results from the accumulation of lipid intermediates in non-adipose tissue, leading to cellular dysfunction and death. The tissues normally affected include the kidneys, liver, heart and skeletal muscle. Lipotoxicity is believed to have a role in heart failure, obesity, and diabetes, and is estimated to affect approximately 25% of the adult American population."
https://en.wikipedia.org/wiki/Lipotoxicity .

Folks that have metabolically health fat mass have adipose tissue that grows by hyperplasia, increase in cell number..

Adiponectin is a very important hormone that is secreted by our adipose tissue..Adiponectin is very insulin sensitizing...also increases our metabolic rate...increases fatty acid oxidation...preserves pancreatic beta-cells...adiponectin promotes glucose-stimulated insulin secretion (GSIS), prevents apoptosis (cell death), and enhances the viability of pancreatic beta-cells under a variety of conditions.

Once you have dysfunctional adipose tissue, your adipocytes release LESS adiponectin and more leptin..Adiponectin is very anti-inflammatory...Leptin is very PRO-inflammatory.

LOW blood adiponectin levels are VERY indicative of T2 diabetes and fatty liver, many other diseases.

Small healthy fat cells release very high levels of adiponectin, very low levels of leptin..

I would need to try and write a few posts about adiponectin, T2D and fatty liver..

Here is a good article on adiponectin:

"Ever since its initial discovery, adiponectin has inspired widespread interest. Readily detectable in blood, stable upon collection and relatively inert to the method of collection and diurnal changes, its levels inversely correlate with multiple metabolic disorders and related diseases. Adiponectin can therefore serve as a potent clinical biomarker in humans and rodents. From the 10,000 studies over the past two decades since its discovery, it is widely appreciated that adiponectin exerts pleiotropic metabolic effects. Adiponectin sensitizes peripheral tissues to insulin and protects against inflammation and apoptosis."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773837/ .

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Systemic metabolic dysregulation Insulin and IGF-1 Dyslipidemia Hyperglycemia Oxidative stress Proinflammatory factors and adipokines Adiponectin Leptin ...

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#78. GIP Prevents Diet-Induced Obesity in Mice | Mirage News

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#80. Proceedings of the 9th International Congress on Obesity

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#81. Eat, Drink or Mate? Here's How Mice Decide

When specific brain receptors sensitive to leptin are stimulated, hungry mice ... It is also thought to play a role between colorectal cancer and obesity.

#82. WeGoTogether® - Wegovy

WEGOVY ® (semaglutide) injection 2.4 mg is an injectable prescription medicine that may help adults and children aged ≥12 years with obesity (BMI ≥30 for ...

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Obesity is a multifactorial chronic disease that has been recognized ... Furthermore, leptin also stimulates the renal secretion of renin, ...

#84. Can Anushka Sharma's 6 pm early dinner routine control ...

Your satiety hormone, leptin, dips late evening, making you hungrier. ... Researchers had 16 overweight patients eat the same exact meals on ...

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But a recent study suggests that you can use Ozempic to help curb excessive weight gain or obesity. Learn more.

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Anti-obesity medication news is seemingly everywhere — from ... proprotein subtilisin-kexin type 1 deficiency or leptin receptor deficiency.

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Gender Differences in Both Spontaneous and Stimulated Leptin Secretion by Human Omental Adipose Tiss... Stimulation of Lipolysis but Not of ...

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“When it comes to diabetes and obesity, poor sleep is often a factor,” says ... Leptin levels typically rise during sleep, so if you aren't ...

#89. Why Eating For Stable Blood Sugar May Help Endometriosis ...

Endometriosis is linked to high leptin levels and low adiponectin levels. Adiponectin22 is anti-inflammatory and helps with insulin sensitivity, ...

#90. World Sleep Day: 5 ways sleeping more may boost weight loss

... a valid strategy for obesity prevention and weight loss programs. ... leading to an increased appetite, and levels of leptin decrease, ...

#91. Do Leptin Supplements Work - Artictle

A review of 25 years of research published in 2019 in Nutrients indicates promise for leptin as a treatment for obesity. "New mechanisms and pathways ...

#92. Best Probiotics For Bloating And Gas 2023 - Outlook India

When leptin levels are high, appetite decreases and it is easier to reduce body weight. Many people who are overweight store extra body fat mass ...

#93. Understanding the price of sleeplessness - Mirchi Plus

People who don't get enough sleep are more prone to put on weight and develop obesity. Leptin and ghrelin, two hormones that control hunger, ...

#94. Do Leptin Supplements Work - Artictle - budnight.co.uk

A review of 25 years of research published in 2019 in Nutrients indicates promise for leptin as a treatment for obesity.